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Ivermectin aglycone is a semi-synthetic produced by the hydrolysis of the disaccharide unit of ivermectin. It is a potent inhibitor of nematode larval development but is devoid of paralytic activity. Ivermectin for sale is an antiparasitic drug. After its discovery in 1975, its first uses were in veterinary medicine to prevent and treat heartworm and acariasis. Approved for human use in 1987, today it is used to treat infestations including head lice, scabies, river blindness (onchocerciasis), strongyloidiasis, trichuriasis, ascariasis and lymphatic filariasis.

It works through many mechanisms to kill the targeted parasites, and can be taken orally, or applied to the skin for external infestations. It belongs to the avermectin family of medications. Wholesale Ivermectin powder

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William Campbell and Satoshi Ōmura won the 2015 Nobel Prize in Physiology or Medicine for its discovery and applications. It is on the World Health Organization’s List of Essential Medicines and is approved by the U.S. Food and Drug Administration as an antiparasitic agent. In 2018, it was the 420th most commonly prescribed medication in the United States, with more than 100,000 prescriptions. It is available as a generic medicine. Buy Pure Ivermectin powder

The aglycone is used as a sensitive probe for the detection of some types of ivermectin resistance. Group: Biochemicals. Alternative Names:

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Dihydroavermectin B1 aglycone,Ivermectin B1 aglycone. Grades: Highly Purified. CAS No. 123997-59-1. Pack Sizes: 1mg. US Biological Life Sciences.
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ProName: Pure Ivermectin powder
CasNo: 70288-86-7
Molecular Formula: C48H74O14
Appearance: white powder
DeliveryTime: 5-7 working days
PackAge: Bottle, Drum, Vacuum Packed, Plastic b…
Port: China major port
ProductionCapacity: 55 Metric Ton/Month
Purity: 99%
Storage: Sealed, dry and refrigerated
Transportation: By Express, Air,Sea
LimitNum: 1 Kilogram
Related Substances: Ivermectin
Residue on Ignition: <5
Heavy Metal: <10ppm
Valid Period: 2 Years
Active Ingredient: Ivermectin
Specification: 99%
Einecs No.: 274-536-0
Application: Health care grade, API
Sample: 5-10g
MOQ: 1KG

Product Description Pure Ivermectin powder

Ivermectin 99% USP36 anti-intestinal parasites Raw Powder Cas 70288-86-7 manufacturer for pets and vets and human!
COA
Product Ivermectin
Testing Item Standard Result
Solubility Partically insoluble in water, freely soluble in methylene chloride, soluble in alcohol Complies
Identification
Ivermectin
1. IR-Should comply
2. HPLC-Should comply
Complies
Appearance of solution Solution is clear ≤ BY7 Complies
Specific Optical Rotation -17° ~ -20° -18.5°
Related Substance a).Impurity (1.3<RRT<1.5) ≤ 2.5%
b).Any other specified impurity ≤ 1.0%
c).Any unspecified impurity ≤ 0.20%
d).Total impurities ≤ 5.0%
a). 2.1%
b).A:0.4%,E:0.2%,H:0.1%,J1:0.4%,J2:0.1%, F or I(RRT0.86):0.1%,For I(RRT1.56):0.1%
c).RRT1.11:0.05%
d).3.6%
Ethanol ≤ 5.0% 3.7%
Formamide ≤ 3.0% 2.3%
Heavy Metal ≤ 0.002% <0.002%
Moisture ≤ 1.0% 0.08%
Sulfated Ash ≤ 0.1% 0.02%
Content (H2B1a+H2B1b) 95.0% ~ 102.0% (Ivermectin) 96.8%
H2B1a/(H2B1a+ H2B1b) ≥ 98.0% 98.2%

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Ivermectin has good effect and safety on nematodes, insects, ticks and other parasites when used in small doses. Launched in 1981, it was quickly used in animal husbandry around the world to protect against nematodes and other infections. It was registered for human use in 1987 and was immediately donated for the treatment of onchocerciasis and lymphatic filariasis. Since its launch, the massive drug donation program has helped 1.5 billion people. The latest figures show that around 186 million people worldwide still need treatment each year, and around 112 million have access to drugs, mainly in the African region. Order Pure Ivermectin powder
Ivermectin is a Food and Drug Administration (FDA)-approved antiparasitic drug that is used to treat several neglected tropical diseases, including onchocerciasis, helminthiases, and scabies. Buy Ivermectin powder

Application

Reports from in vitro studies suggest that ivermectin acts by inhibiting the host importin alpha/beta-1 nuclear transport proteins, which are part of a key intracellular transport process that viruses hijack to enhance infection by suppressing the host’s antiviral response.4,5 In addition, ivermectin docking may interfere with the attachment of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein to the human cell membrane.6 Ivermectin is thought to be a host-directed agent, which may be the basis for its broad-spectrum activity in vitro against the viruses that cause dengue, Zika, HIV, and yellow fever.4,7-9 Despite this in vitro activity, no clinical trials have reported a clinical benefit for ivermectin in patients with these viruses. Wholesale Buy ivermectin powder CAS 70288-86-7

Some studies of ivermectin have also reported potential anti-inflammatory properties, which have been postulated to be beneficial in people with COVID-19.10-12
Some observational cohorts and clinical trials have evaluated the use of ivermectin for the prevention and treatment of COVID-19. Data from some of these studies .

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In the past 30 years, ivermectin has played an outstanding role in the fight against parasitic diseases, saving millions of lives, which is a glorious page of the modern pharmaceutical industry. With the rapid development of medical technology, parasitic diseases, bacterial infections and viral infections have been controlled. At present, cancer, cardiovascular and cerebrovascular diseases, diabetes and other chronic diseases have become the primary factors threatening human health. In order to cope with the dilemma, biotechnology advances rapidly, and various new antibody drugs spring up like mushrooms. As we carefully develop new drugs, let’s not forget the old ones, such as ivermectin, which have shown extraordinary promise in many disease domains. The new use of old medicine may also be a new way of medical innovation. Wholesale Pure Ivermectin powder

Recommendation:

There is insufficient evidence for the COVID-19 Treatment Guidelines Panel (the Panel) to recommend either for or against the use of ivermectin for the treatment of COVID-19. Results from adequately powered, well-designed, and well-conducted clinical trials are needed to provide more specific, evidence-based guidance on the role of ivermectin in the treatment of COVID-19. Wholesale Buy ivermectin powder CAS 70288-86-7